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临床试验/CTRI/2026/03/107044
CTRI/2026/03/107044尚未招募2/3 期

Comparison of postoperative analgesia by ropivacaine and bupivacaine for ultrasound-guided adductor canal block in arthroscopic knee surgery

Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital1 个研究点 分布在 1 个国家目标入组 72 人开始时间: 2026年4月10日最近更新:
适应症
相关药物

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
72
试验地点
1
主要终点
Duration of postoperative analgesia i.e. time at which first rescue analgesic required i.e. when NRS at rest is more than 4

研究概览

简要总结

This is a comparative interventional study to evaluate and compare the postoperative analgesia by ropivacaine and bupivacaine for ultrasound-guided adductor canal block in arthroscopic knee surgery. After obtaining Institutional Ethics Committee approval and written informed consent from patients, all patients meeting inclusion criteria will be enrolled in the study.

For adductor canal block, patient will be placed in supine position with knee slightly flexed on the side of surgery. A high frequency linear ultrasound transducer will be placed on the medial surface in midline of the thigh in the transverse plane. After visualisation of the pulsatile superficial femoral artery dorsal to the sartorial muscle, probe will be moved distally and saphenous nerve will be visualised as a hyperechoic structure anterolateral to the artery in subsartorial region. Using the in-plane technique, injection site will be confirmed with an injection of 5 ml of saline, and then 20 ml of 0.25% ropivacaine or 20 ml of 0.25% bupivacaine will be injected in Group R and Group B respectively.

After performing the block, hemodynamic parameters will be monitored and patient will be assessed for any adverse effects like local hematoma or any hemodynamic variations. In PACU, patient will be assessed at arrival and thereafter at 1, 3, 6 ,12, 18 and 24 hours for pain using Numerical Rating Scale(NRS) at rest and on movement. Injection tramadol 50 mg intravenous will be given as rescue analgesia when NRS at rest > 4. Time of requirement of first rescue analgesia and total dose of tramadol required in first 24 hours will be noted. Quadriceps muscle strength will be assessed using MMT Score(Manual Muscle Testing Score).

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant and Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • ASA physical status 1 or 2, scheduled for elective arthroscopic knee surgery under spinal anaesthesia.

排除标准

  • Patients on chronic analgesic therapy Coagulopathy Infection at block site Allergy to local anaesthetics Polytrauma patients.

结局指标

主要结局

Duration of postoperative analgesia i.e. time at which first rescue analgesic required i.e. when NRS at rest is more than 4

时间窗: 0,1,3,6,12,18 and 24 hours

次要结局

  • Total Dose of Rescue Analgesic required in first 24 hours(24 hours)
  • Quadriceps muscle strength using MMT Score(0,1,3,6,12,18 and 24 hours)
  • Adverse effects like local site hematoma and hemodynamic variations(0,1,3,6,12,18 and 24 hours)

研究者

发起方
Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Rakshit Singh

ABVIMS and Dr. Ram Manohar Lohia Hospital, New Delhi

研究点 (1)

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