A clinical study of Natrum group in cases of Acne Vulgaris by GAGS Scale
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- For the effective assessment and evaluation, disease intensity scores will also be
研究概览
简要总结
• Acne vulgaris is a common cutaneous inflammatory disorder of the pilosebaceous unit, which runs a chronic course. The condition commonly manifests with papules, pustules, or nodules primarily on the face, although it can also affect the upper arms, trunk, and back.
• The severity of this condition can vary, ranging from a mild presentation with only a few comedones to more severe forms characterized by disfiguring inflammatory manifestations, which can lead to hyperpigmentation, scarring, and adverse psychological effects.
• Acne is estimated to affect 9.4% of the global population, making it the eighth most prevalent disease worldwide.
• Acne is one of the most common skin disorders worldwide, with an estimated global prevalence of 9.38%. According to the Global Burden of Diseases (GBD) study, acne affects ~85% of young adults.
• However, there are instances where acne can persist into adulthood or even develop for the first-time during adulthood.
• Better understanding of factors affecting acne vulgaris may, therefore, serve to identify patients needing special attention.
• Acne tends to be chronic, and is obstinately resistant to treatment. Moreover, it is subjected to periods of aggravation without treatment of any kind. Available management in Allopathy includes topical agents; benzoyl peroxide, antibiotics, retinoids, etc. as the mainstay of treatment; these can be given in combinations. While systemic therapy includes oral antibiotics, hormonal therapy, and isotretinoin but have not much relief.
• The treatment comes with known side effect such as irritant dermatitis, development of bacterial resistance.
• In Homoeopathic Natrum group medicines emphasize individualization based on specific personality and emotional traits. This personalized approach could potentially address the underlying emotional and stress factors that may contribute to acne vulgaris, offering a more holistic treatment approach.
• Psychosomatic manifestation play a major role in acne like low self-esteem, social isolation and anxiety due to look consciousness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 12.00 Year(s) 至 25.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients irrespective of their caste, religion and socio-economic condition.
- •Pre-diagnosed cases of acne vulgaris or newly added cases having a diagnosis of Acne vulgaris.
排除标准
- •Patients having a age under 12 and more than 25 years will be excluded Pregnant and lactating mother.
- •Patients with other systemic illness or serious pathological condition.
- •Patients complain complicated with other skin disease.
- •Patients with other acne types.
- •Patients taking other therapeutic measures for Acne vulgaris or any other disease.
结局指标
主要结局
For the effective assessment and evaluation, disease intensity scores will also be
时间窗: After the intervention, the first follow-up will take place in 15 days, followed by subsequent follow-ups every 15 days. There will be some improvement after prescribing the Natrum group of Homoeopathic Medicines.
maintained according to GAGS- Score.
时间窗: After the intervention, the first follow-up will take place in 15 days, followed by subsequent follow-ups every 15 days. There will be some improvement after prescribing the Natrum group of Homoeopathic Medicines.
次要结局
- Clinical improvement - Disappearance or relief of symptoms, improvement in general health & reduction in area spread.(There will be some improvement after prescribing Natrum group of Homoeopathic Medicines, noticeable during the first follow-up after 15 days.)
研究者
Dr Jyotiben Naranbhai Balas
Rajkot Homoeopathic Medical College