Correlation Between Complications of Pre-eclampsia and Detection of Novel Biochemical Markers
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- The level of circulating NGAL
研究概览
简要总结
In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney impairment characteristics, a recent study demonstrated that the serum levels of NGAL increased at the end of the second trimester in women who subsequently developed pre-eclampsia compared to the control group.
This correlates well with the endothelial damage that occurs during pre-eclampsia and thus NGAL can be considered as a promising marker in predicting both early and late onset pre-eclampsia. It may be required to combine one or more biomarker with NGAL to increase the precision, and sensitivity for detection of risk and reliability of using biomarkers for pre-eclampsia.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age 20-40 years.
- •Gestational age >20 weeks.
排除标准
- •Patients with preexisting renal disease,hypertension, diabetes mellitus, gestational hypertension.
- •Patients Refuse to participate in the study
- •Patients already have complicated preeclampsia.
结局指标
主要结局
The level of circulating NGAL
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Ahmed Mohamed Abbas
Lecturer
Assiut University