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临床试验/NCT03860103
NCT03860103已完成不适用

Placental Insufficiency Microcirculation Quantification by Ultrafast Doppler: an Observational Prospective Study

Nantes University Hospital1 个研究点 分布在 1 个国家目标入组 165 人开始时间: 2019年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
165
试验地点
1
主要终点
Qualitative analysis (velocities) of intraplacental blood flow after acquisition of sequences in Ultrafast Doppler imaging

研究概览

简要总结

To identify fetuses small for their gestational-age who have reached their appropriate growth potential from growth-restricted fetuses due to placental insufficiency is uneasy. Intra Uterine Growth Restriction (IUGR) increases the risk for indicated preterm delivery, neonatal mortality and morbidity. Therefore, improving the knowledge of the placental perfusion is essential to better identify and manage fetal chronic oxygen deprivation associated with placental insufficiency. Thus, the investigators propose to study placental microcirculation with a more efficient Doppler than conventional Doppler use in clinical practice. The Ultrafast Doppler is being able to map placental blood flow and could have potential impact in placental insufficiency diagnosis and prevention. Moreover, this Doppler could discriminate maternal and fetal vascularization.

The hypothesis is that Ultrafast Doppler could help clinician to diagnose and manage preeclampsia and IUGR during pregnancy.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
Female
接受健康志愿者
是

入选标准

  • •Patient who accepted to participate in the study
  • •Woman over 18 years old
  • •Affiliated to a social security scheme
  • •Mono-fetal pregnancy
  • •Patients with normal pregnancy between 11 and 42 weeks of amenorrhea
  • •Patients hospitalized for preeclampsia and / or intrauterine growth retardation, beyond 20 weeks of amenorrhea

排除标准

  • •Minors, adults under guardianship, protected persons
  • •Not affiliated to a social security scheme
  • •Multiple pregnancy

结局指标

主要结局

Qualitative analysis (velocities) of intraplacental blood flow after acquisition of sequences in Ultrafast Doppler imaging

时间窗: from the 12 week of gestation

Quantitative analysis (flow rates) of intraplacental blood flow after acquisition of sequences in Ultrafast Doppler

时间窗: from the 12 week of gestation

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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