Accuracy of autofluorescence in Parathyroid adenoma – A diagnostic study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- To study the clinical utility of Autofluorescence as a technique of intraoperative localization in Parathyroid Adenoma
研究概览
简要总结
The study is a single institutional diagnostic study, conducted at Department of Surgical Disciplines, AIIMS, New Delhi. The patients included in inclusion criteria will be recruited and will undergo pre-operatively history taking, examination and pre-operative blood investigations (CBC, LFT, RFT, intact PTH, Vitamin D3, serum Calcium), Radiological Investigations like USG-Neck, SESTAMIBI/SPECT, 4D-CT, DEXA Scan, X-Ray forearm.
Intra-operatively during parathyroidectomy hemi or total thyroidectomy using Near Infrared Autofluorescence device will be used to identify parathyroid gland . The autofluorescence pattern will be recorded as homogenous or heterogenous. In resected specimens during parathyroidectomy presence of single well defined bright autofluoroscent region will be identified as a cap and indicated with a surgical marker. The specimen of parathyroid will be sent for histopathology and the diagnosis is confirmed.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •patient with parathyroid adenoma.
排除标准
- •Patients with parathyroid hyperplasia.
结局指标
主要结局
To study the clinical utility of Autofluorescence as a technique of intraoperative localization in Parathyroid Adenoma
时间窗: 1 year 9 months
次要结局
- to compare the auto fluorescence patterns in parathyroid adenoma & normal parathyroid gland during focused parathyroidectomy & hemi or total thyroidectomy respectively using infrared imaging system(1 year 9 months)
研究者
Ayush Gupta
All India Institute Of Medical Sciences Delhi,