Central and Peripheral Changes in Quadriceps Femoris Function After Different Types of Isometric Strength Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 52
- 试验地点
- 1
- 主要终点
- Motor Evoked Potentials (MEP)
研究概览
简要总结
The purpose of this investigation is to examine the effects of 6-week unilateral isometric training interventions over quadriceps femoris on maximal strength and RFD-SF parameters and cortical excitability. Isometric strength training involved either electromyostimulation, voluntary activation, or the combination of both. The second aim is to investigate the potential cross-over effect on a non-trained leg.
详细描述
A longitudinal pre-post design with random assignment of the participants to one of three experimental groups or the control group was used. Quadriceps femoris (QF) function and cortical excitability were assessed on four occasions: prior to the intervention (pre-test), after 3 weeks of training (served for the adjustment of exercise intensity), after 6 weeks of training (post-test), and three weeks after the competition of training intervention (detraining) (Figure 1). Isometric strength training involves activation of QF applying EMS, VOLUNTARY, or the combination of both EMS and VOLUNTARY (COMBINED). The pre-test also served to familiarize participants with the training protocols and to determine the intensity of EMS needed to achieve 60%MVC. Quadriceps femoris (QF) function was assessed by MVC and RFD-SF. Cortical excitability was assessed with transcranial magnetic stimulation applied over the M1 region. Prior to the pretest, body mass and percent of body fat were assessed using a bioelectric impedance method (In Body 720; USA) and body height with a standard stadiometer. After the pretest, the participants were randomly assigned to either one of the experimental groups (EMS, VOLUNTARY, or COMBINED) and the control group (CONTROL). Experimental groups performed unilateral isometric strength training three times per week for 6 weeks. All participants were advised to refrain from all resistance training targeting the legs between pre-test and post-test.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 30 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •young healthy, physically active participants of both genders
排除标准
- •no history of injuries, muscle-skeletal or neurological disease, or medications intake
研究组 & 干预措施
Electromyostimulation - EMS
Experimental group comprised of healthy young adults that undergoes unilateral isometric training using electromyostimulation over quadriceps femoris
干预措施: Isometric training with electromyostimulation (Other)
Voluntary activation - VOLUNTARY
Experimental group comprised of healthy young adults that undergoes unilateral isometric training based on voluntary activation of quadriceps femoris
干预措施: Isometric training with voluntary activation (Other)
Combination of EMS and VOLUNTARY - COMBINED
Experimental group comprised of healthy young adults that undergoes unilateral isometric training that combines electromyostimulation and voluntary activation of quadriceps femoris.
干预措施: Isometric training with combination of electromyostimulation and voluntary activation (Other)
Control group - CONTROL
Group of healthy young adults who received no intervention.
结局指标
主要结局
Motor Evoked Potentials (MEP)
时间窗: After 9 weeks
MEPs were elicited in quadriceps femoris by transcranial magnetic stimulation (TMS) over M1 area. Motor cortex excitability was estimated by measuring the MEP amplitude (Input-Output, IO) peak to peak, caused by 20 randomized individual TMS stimulates with 100% (IO1), 120% (IO2) and 130% (IO3) of active motor threshold (AMT) intensity.
MVC
时间窗: After 9 weeks
Maximal isometric force and Rate of Force Development of quadriceps femoris muscle during isometric contractions with maximal effort
The slope of the rate-of-force development scaling factor (RFD-SF)
时间窗: After 9 weeks
The slope of the relationship (RFD-SF) between muscle force and rate of force development during rapid isometric contractions of varying intensities
MVC
时间窗: Baseline
Maximal isometric force and Rate of Force Development of quadriceps femoris muscle during isometric contractions with maximal effort
MVC
时间窗: After 3 weeks
Maximal isometric force and Rate of Force Development of quadriceps femoris muscle during isometric contractions with maximal effort
MVC
时间窗: After 6 weeks
Maximal isometric force and Rate of Force Development of quadriceps femoris muscle during isometric contractions with maximal effort
The slope of the rate-of-force development scaling factor (RFD-SF)
时间窗: Baseline
The slope of the relationship (RFD-SF) between muscle force and rate of force development during rapid isometric contractions of varying intensities
The slope of the rate-of-force development scaling factor (RFD-SF)
时间窗: After 3 weeks
The slope of the relationship (RFD-SF) between muscle force and rate of force development during rapid isometric contractions of varying intensities
The slope of the rate-of-force development scaling factor (RFD-SF)
时间窗: After 6 weeks
The slope of the relationship (RFD-SF) between muscle force and rate of force development during rapid isometric contractions of varying intensities
Motor Evoked Potentials (MEP)
时间窗: Baseline
MEPs were elicited in quadriceps femoris by transcranial magnetic stimulation (TMS) over M1 area. Motor cortex excitability was estimated by measuring the MEP amplitude (Input-Output, IO) peak to peak, caused by 20 randomized individual TMS stimulates with 100% (IO1), 120% (IO2) and 130% (IO3) of active motor threshold (AMT) intensity.
Motor Evoked Potentials (MEP)
时间窗: After 3 weeks
MEPs were elicited in quadriceps femoris by transcranial magnetic stimulation (TMS) over M1 area. Motor cortex excitability was estimated by measuring the MEP amplitude (Input-Output, IO) peak to peak, caused by 20 randomized individual TMS stimulates with 100% (IO1), 120% (IO2) and 130% (IO3) of active motor threshold (AMT) intensity.
Motor Evoked Potentials (MEP)
时间窗: After 6 weeks
MEPs were elicited in quadriceps femoris by transcranial magnetic stimulation (TMS) over M1 area. Motor cortex excitability was estimated by measuring the MEP amplitude (Input-Output, IO) peak to peak, caused by 20 randomized individual TMS stimulates with 100% (IO1), 120% (IO2) and 130% (IO3) of active motor threshold (AMT) intensity.
次要结局
- M-wave(After 9 weeks)
- The linearity of the rate-of-force development scaling factor (RFD-SF) relationship(After 9 weeks)
- The linearity of the rate-of-force development scaling factor (RFD-SF) relationship(Baseline)
- The linearity of the rate-of-force development scaling factor (RFD-SF) relationship(After 3 weeks)
- The linearity of the rate-of-force development scaling factor (RFD-SF) relationship(After 6 weeks)
- M-wave(Baseline)
- M-wave(After 3 weeks)
- M-wave(After 6 weeks)
研究者
Dragan Mirkov
Professor Dr.
University of Belgrade