Analgeisc Effect of Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block in Patients Undergoing Open Abendectomy Surgery: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Total morphine consumption
研究概览
简要总结
this aim of this study is to compare the analgesic effect of Erector spinae plane (ESP) block and lateral transversus abdominis plan (TAP) block in patients undergoing open appendectomy.
详细描述
regional technique according to randomization will be given after induction of general anesthesia Fentanyl boluses of 1 mcg/kg will be given in case of inadequate analgesia. Inadequate analgesia identified by 20% increase in the heart rate and/or systolic blood pressure from baseline measurement.
postoperative analgesia: regular paracetamol 1 g/6 hours (intravenously at first then orally once the oral feeding is resumed) and 75 mg diclofenac (intramuscularly at first then orally once the oral feeding is resumed).
If Numeric rating scale (NRS) is > 3 intravenous titration of 2 mg morphine is given slowly to be repeated after 30 minutes if pain persisted
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients, undergoing open appendectomy.
排除标准
- •American society of anesthesiologist-physical status >III,
- •allergy to any of the study drugs,
- •coagulopathy
- •local infection,
- •history of chronic pain or regular opioid use;
- •inability to comprehend the Numeric Rating Scale (NRS),
- •pregnant or lactating women.
研究组 & 干预措施
ESP group
干预措施: Erector Spinae Plane Block (Other)
TAP group
干预措施: Transversus abdominis plane (TAP) block (Other)
结局指标
主要结局
Total morphine consumption
时间窗: from extubation until 24 hours postoperative
mg
次要结局
- numeric rating scale(AT 0.5, 2, 6, 12, and 24 hours postoperative.)
- quality of recovery(24 hours after suregry)