Effect of human umbilical cord Wharton’s jelly-derived Mesenchymal stem cells exosomes in treatment of dry eye disease in primary sjogren’s syndrome

Shiraz University of Medical Sciences0 个研究点目标入组 5 人开始时间: 待定最近更新: 2022年5月2日

试验速览

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•Middle-aged women between the ages of 45 and 35 with dry eye
•Clinically and serologically diagnosed by an ophthalmologist, rheumatologist or internal medicine specialist with sjogren’s syndrome.
•Previous use of artificial tears can not relieve it.
•Symptoms of dry eye in at least one patient's eye include redness, dryness, burning sensation, foreign body sensation, eye discomfort, or visual fatigue.
•Tear discharge test (Schermer test) both eyes = 10 mm / 5 min
•Tear break time (TBUT) will be less than 10 seconds.

•People who are allergic to any drug .
•Pregnant or lactating women .
•Patients with active fungal, bacterial or viral keratitis or conjunctivitis.
•People with serious heart, lung, liver or kidney disease or other incurable eye diseases such as glaucoma, uveitis.
•People who wear contact lenses and do not want to remove them in the study.
•Perform eye surgery (including cataract surgery) in the last three months.
•Simultaneous enrollment in other interventional clinical trials.
•Use of eye drops in the last 24 hours that may affect the clinical study.
•They have serious systemic diseases.

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