NCT02519751已完成不适用
Total Body Skeletal Muscle Mass Estimation by Creatine (Methyl-d3) Dilution in Athletes
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Correlation between muscle mass obtained by MRI method and D3-Creatine method
研究概览
简要总结
Creatine (methyl-d3) dilution (D3-creatine) is a novel technique for the estimation of muscle mass. The method uses a dose of deuterium-labelled creatine to determine total skeletal muscle mass via estimation of total body creatine pool size.The aim of this study is to compare estimates of total body skeletal muscle mass by D3-creatine dilution method and whole body Magnetic Resonance Imaging (MRI) in an athletic population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Trained and competing elite canoe athletes will be recruited, who represent Great Britain Canoeing
排除标准
- •Pregnant and lactating women
- •Intolerance or hypersensitivity to Creatine supplementation
- •Athletes with disabilities which affect their total body muscle mass
- •If creatine was taken in a supplemented form, rather than dietary intake, more regularly than once a week within 6-weeks of assessment commencing
- •Contraindication to an MRI scan
结局指标
主要结局
Correlation between muscle mass obtained by MRI method and D3-Creatine method
时间窗: Upto 3 months
MRI scan of the participants will be done at Day 1 and end of study (i.e.Day 90).D3-Creatine capsule will be given orally at Day 1 and urine samples collected at 0-4h and 4-24h every day from Day 1 to Day 4.
次要结局
未报告次要终点
研究者
研究点 (2)
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