Evaluation of Adults With Endocrine-Related Conditions
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,250
- 试验地点
- 1
- 主要终点
- Recruit a diverse population of adult subjects with a known or suspected endocrine or metabolic disorder in order to provide NIDDK investigators and trainees with hands-on experience related to the diagnosis, management, treatment, and follow-up...
研究概览
简要总结
Background:
There are many endocrine and metabolic-related conditions. Two well-known disorders include diabetes and thyroid disease. Some of these diseases are caused by a change in genes. Researchers want to identify the genes involved in these disorders. They hope this will help them learn more about these diseases.
Objectives:
To learn more about conditions that affect the hormone-secreting glands (endocrine glands) in adults. To train doctors to diagnose and treat people with endocrine or metabolic conditions.
Eligibility:
Adults age 18 years and older with a known or suspected endocrine disorder.
Relatives ages 18 years and older.
Doctors will review all requests and available medical records to determine final eligibility for the protocol.
Design:
Participants will have a medical history and physical exam.
Most participants will have 1 visit, and may have follow up visits if necessary. They may have tests, surgery, or other procedures to help diagnose or treat their condition. These could include:
- Blood, urine, and saliva tests
- Imaging tests. These may include X-ray, ultrasound, or scans.
- Sleep study
- Medical photographs
- Visits with other specialists at NIH
Participants will provide blood, urine, saliva, or tissue samples. Some of these samples may be stored in the freezer for future studies.
Participants may be asked to participate in genetic testing. They will give a blood or saliva sample for this.
详细描述
This is an observational protocol designed to collect data from adult subjects with known or suspected endocrine or metabolic disorders.
OBJECTIVE
The overall purpose of endocrine evaluations under this protocol is to increase knowledge of endocrine or metabolic diseases. Adults with known or suspected endocrine or metabolic-related condition(s) may be evaluated under this protocol for:
- Collection of data for endocrine related conditions (case reports, case series)
- Collection of data for future research
- Collection of samples, including leftover samples from clinically indicated tests, for future research (including genomics)
METHODS: Patients will undergo a history and physical exam, anthropometrics, vital signs and endocrine laboratory studies.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •INCLUSION CRITERIA:
- •Participants with known or suspected endocrine disorder age 18 years and older are eligible for this protocol. Protocol investigators will make the actual selection of subjects most appropriate for clinical evaluation.
- •Relatives ages 18 years and older may be enrolled if clinically indicated for the diagnosis of a proband.
排除标准
- •Anyone under the age of 18 years old
- •Any medical, physical, psychiatric, or social conditions, which, in the opinion of the investigators, would make participation in this protocol not in the best interest of the subject. Subjects who are critically ill, unstable, or with severe organ failure that may affect/limit the endocrine evaluation and place unsustainable demands on Clinical Center or NIDDK resources.
研究组 & 干预措施
Adults with known or suspected endocrine or metabolic dissorde
Adults with known or suspected endocrine or metabolic dissorders
结局指标
主要结局
Recruit a diverse population of adult subjects with a known or suspected endocrine or metabolic disorder in order to provide NIDDK investigators and trainees with hands-on experience related to the diagnosis, management, treatment, and follow-up...
时间窗: 12/31/2036
The overall purpose of endocrine evaluations under this protocol is to support our clinical training and research missions.
次要结局
未报告次要终点