ISRCTN46523456已完成不适用
A randomised controlled trial evaluating the effects of hormone replacement therapy (HRT) on bone mineral density (BMD) and disease course in postmenopausal women with rheumatoid arthritis (RA)
Sahlgrenska Academy at Göteborg University (Sweden)0 个研究点目标入组 88 人开始时间: 2004年4月22日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 88
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Postmenopausal women with RA between 45 and 55 years old
- •2. Active disease, which met at least two of the following criteria:
- •2.1. At least six painful joints
- •2.2. At least three swollen joints
- •2.3. Erythrocyte sedimentation rate (ESR) at least 20 mm per hour
- •2.4. C-reactive protein (CRP) at least 10 mg/l
- •2.5. Fulfils the American Rheumatism Association 1987 revised criteria for adult RA
- •3. A maximum daily dose of 7.5 mg of prednisolone was accepted
- •4. Not receiving, or had not been using in the past two years, drugs affecting bone metabolism (HRT or bisphosphonates), except calcium and vitamin D3, which were allowed
- •5. No contra-indications to HRT
排除标准
- •Does not comply with above inclusion criteria.
研究者
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