Effect of cognitive behavioural therapy for insomnia and/or chronobiological therapy on depressive symptoms in persons with insomnia prone to depression

etherlands Institute for Neuroscience0 个研究点目标入组 120 人开始时间: 待定最近更新: 2024年6月11日

适应症

试验速览

暂无简介。

•1. Age ≥ 18 years and < 70 years
•2. Diagnosis of insomnia according to the International Classification of Sleep Disorders (ICSD-3) and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V).

•1. A current clinical diagnosis of major depressive disorder or a diagnosis of major depressive assessed with the Composite International Diagnostic Interview – Short Form (CIDI-SF).
•2. People in whom symptoms of obstructive sleep apnea syndrome (OSAS), restless legs syndrome (RLS) and periodic limb movement disorder (PLMD), are a major cause of disturbed sleep will be excluded. First, we will ask people if they have been clinically diagnosed with one of these sleep disorders. If they have been diagnosed indeed, they will be excluded in case of a polysomnographically assessed apnea hypopnea index (AHI) of 15 or more or periodic limb movement index (PLMI) of 25 or more. Second, using the screener survey, we will exclude candidates with moderate to very severe RLS according to an IRLS scale score > 15 17 and candidates with a high risk of OSAS according to the Berlin questionnaire. In candidates suspect for PLMD according to the Duke Structured Interview for Sleep Disorders, the PLMI will be determined from the polysomnographic recordings of the pre-assessment; cases with a PLMI ≥ 25 will be advised to consult a sleep specialist.

发起方

etherlands Institute for Neuroscience