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临床试验/NCT01516697
NCT01516697撤回4 期

Using Thoracic Electrical Bioimpedance to Measure Stroke Volume and Cardiac Output in Patients Under Spinal Anesthesia for Cesarean Section

Massachusetts General Hospital2 个研究点 分布在 1 个国家开始时间: 2011年10月最近更新:
适应症

试验速览

阶段
4 期
状态
撤回
试验地点
2
主要终点
Maximum percentage changes in mean blood pressure after spinal anesthesia

研究概览

简要总结

The investigators hypothesize that continuously measuring stroke volume (SV) and cardiac output (CO) will 1) reveal hemodynamic instability in a timely manner and alert the physician promptly, 2) provide information for the physician to make the differential diagnosis as to whether the hemodynamic instability was due to vasodilatation or reduction of venous blood return, and 3) lead to appropriate and prompt treatment to improve patient outcome.

-determine the SV and CO and their kinetic change using ICON® to establish a hemodynamic profile of the patient under spinal anesthesia for cesarean section. To determine if using instantaneous measurements of SV and CO to guide patient management improves hemodynamic stability.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • age 18-45;
  • receiving spinal anesthesia or combined spinal and epidural anesthesia to undergo cesarean section

排除标准

  • Patients who have major cardiovascular disease,preexisting of hypertension or gestational hypertension, preeclampsia and body mass index greater than 35kg/m2;
  • Patients who have skin lesion at the place where the electrode is supposed to be applied;
  • Emergency cesarean section patients.

结局指标

主要结局

Maximum percentage changes in mean blood pressure after spinal anesthesia

时间窗: baseline before spinal anesthesia and up to 20 minutes after spinal anesthesia

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yandong Jiang

Assistant professor

Massachusetts General Hospital

研究点 (2)

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