A Observational Cohort Study to Identify Risk Factors for Post Operative Nausea and Vomiting Following General Anesthesia in Female Patient Underwent Gynecological Operation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 774
- 试验地点
- 1
- 主要终点
- Incidence of postoperative nausea and vomiting
研究概览
简要总结
Risk factors for postoperative nausea and vomiting(PONV) such as past history of PONV and/or motion sickness, non-smoking status, female gender, planned opiate use for post-operative analgesia were identified in white people. Whereas, risk factors for PONV in female patient with mongolian race were not clear. As a different life style and genetic background, new risk factors may associate with PONV in this population. The present study is a prospective cohort study to identify risk factors for PONV within 24 postoperative hours in chinese female patients underwent gynecology operative under general anesthesia.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •>18 years old
- •Chinese female patient
排除标准
- •Unstable vital sign
- •Patients under mechanical ventilation
- •Patients under sedition (RASS=<-2)
结局指标
主要结局
Incidence of postoperative nausea and vomiting
时间窗: within 24 postoperative hours
次要结局
- Incidence of postoperative shivering(within 24 postoperative hours)
- Postoperative pain score with Numerical Rating Scale (NRS-11)(within 24 postoperative hours)
- Time to full recovery of intestinal function(within 24 postoperative hours)
- Preoperative and postoperative fasting time(within 24 postoperative hours)
- Length of postoperative hospital stay and Length of hospital stay(before discharge)
- Total health care costs(before discharge)
- Postoperative delirium in recovery room(within PACU stay)
研究者
Wei Mei
Associate Professor
Huazhong University of Science and Technology