NCT00746928Unknown不适用
Cardiovascular Consequences of Intermittent Hypoxia in Healthy Subjects
University Hospital, Grenoble2 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2005年9月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- Blood Pressure
研究概览
简要总结
The study is a prospective field evaluation to assess the effects of the chronic Intermittent Hypoxia exposure in 12 healthy humans.
Precisely, the study was designed to :
Set up a new model of Chronic Intermittent Hypoxia (CIH) applied to healthy human. This CIH is mimicking the CIH undergone by patients suffering from Sleep Apnea Syndrome.
Evaluate the cardiovascular effect of CIH. Neuronal and humoral sympathetic control, blood pressure control, vascular resistance.
Evaluate the Sleep quality, the ventilation under exposure and the long terms effect on ventilation control of CIH (central and peripheral chemoreflex).
Investigates the biological aspects of CIH exposure.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy subjects
排除标准
- •Any history or significant medical condition
结局指标
主要结局
Blood Pressure
时间窗: Two Weeks
次要结局
- The ventilation under exposure and the long terms effect on ventilation control of CIH (central and peripheral chemoreflex)(two weeks)
- Sleep quality(Two Weeks)
- Neuronal and humoral sympathetic control and vascular resistance.(Two weeks)
研究者
研究点 (2)
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