ACTRN12612001069842终止2 期
The effect of timed co-ordinated vaccine and chemotherapy delivery on complete response rate and overall survival in patients with advanced melanoma
Australian Melanoma Research Foundation0 个研究点目标入组 20 人开始时间: 2012年10月5日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 终止
- 发起方
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 80 Years（—）
- 性别
- All
入选标准
- •18 - 80 years of age. ECOG 0-2. Evaluable metastases. Primary cutaneous melanoma. Advanced surgically non-resectable AJCC Stage IIIB/IIIC or IV. Able to give informed consent. Tumour volume < 20cm diameter or <70% of organ replacement.
排除标准
- •Presence of another primary invasive cancer (not BCC, SCC or resected in-situ malignancy)
- •Untreated brain mets
- •Extremely extensive disease
- •Bone mets only
- •High dose oral steroid therapy
- •Pregnancy or lactation
- •Severe atopia
- •Severe cachexia
- •Immunodeficiency
- •Hep B or C +ve
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