The Efficacy of Ultrasound Guided Sphenopalatine Ganglion Block as Adjuvant to General Anesthesia Regarding the Quality of Surgical Field in Trans-Sphenoidal Endoscopic Hypophysectomy: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
- 试验地点
- 1
研究概览
简要总结
This study aims to evaluate the efficacy of ultrasound guided sphenopalatine ganglion block (SPGB) through the suprazygomatic approach in optimizing the quality of surgical field as well as its effect on postoperative pain relief in patients undergoing transsphenoidal pituitary surgeries under general anesthesia.
详细描述
The main surgical treatment for pituitary adenomas is endoscopic trans-sphenoidal hypophysectomy.
Among the many regional blocks used is the sphenopalatine ganglion block (SPGB). It is one of the parasympathetic ganglia in the head, located in the pterygopalatine fossa, posterior to the middle nasal turbinate, 1-5 mm deep to the mucosa, anterior to the pterygoid canal and lateral to the sphenopalatine foramen.
This superficial location makes it easy to block the ganglion transnasally by topical anesthesia or by injection through many approaches including transnasal, intraoral, infrazygomatic and suprazygomatic approaches.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Months 至 60 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 21 and 60 years.
- •American Society of Anesthesiologists (ASA) Physical Status I or II.
- •Undergoing elective endoscopic trans-nasal resection of pituitary adenoma.
排除标准
- •Patient's refusal
- •ASA Physical Status III or IV patients
- •Patients receiving drugs influencing blood coagulation
- •Allergy to any of the drugs utilized in this study
- •History of chronic pain therapy
- •Inadvertent intra-operative vascular injury
研究组 & 干预措施
Group A
Patients will receive sphenopalatine ganglion block (SPGB) using 4 mL of 0.25% bupivacaine combined with 1 mL of dexamethasone .
干预措施: Sphenopalatine ganglion block using bupivacaine + dexamethasone (Drug)
Group B
Patients will receive general anesthesia alone.
干预措施: General anesthesia (Other)
研究者
Nada Ashraf Mohamed Fathy
Assistant Lecturer of Anesthesiology, Surgical ICU and Pain Management, Cairo University, Cairo, Egypt.
Cairo University