NCT00848562已完成不适用
Oral Nicorandil to Reduce Cardiac Death After Coronary Revascularization in Hemodialysis Patients: A Randomized Trial
Toujinkai Hospital1 个研究点 分布在 1 个国家目标入组 129 人开始时间: 2002年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 129
- 试验地点
- 1
- 主要终点
- Cardiac death (sudden cardiac death, deaths due to acute myocardial infarction or congestive heart failure)
研究概览
简要总结
Survival after invasive coronary revascularization is worse in patients with chronic kidney disease than in those without it. The investigators aimed to examine whether oral administration of nicorandil, a hybrid of nitrate and adenosine triphosphate-sensitive potassium channel opener, could improve the survival of end-stage renal disease patients with coronary artery disease by inhibiting cardiac death after coronary revascularization.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hemodialysis patients with coronary artery disease who had undergone a successful first PCI with bare-metal stents between July 1, 2001 and December 31, 2003.
排除标准
- •Subjects with moderate or worse cardiac valvular disease or old myocardial infarction at the point of first PCI.
研究组 & 干预措施
Nicorandil
Experimental
干预措施: Nicorandil (Drug)
结局指标
主要结局
Cardiac death (sudden cardiac death, deaths due to acute myocardial infarction or congestive heart failure)
时间窗: Jan 1, 2002 to Dec 31, 2006
次要结局
- All-cause mortality(Jan 1, 2002 to Dec 31, 2006)
研究者
研究点 (1)
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