NL-OMON42260已完成不适用
Pilot study: The retina as a potential window to visualize neuropathology in Alzheimer's disease. - Is Alzheimer's disease visible in the eye?
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Study cases: Patients with early onset (<70 years) AD according to the NINCDS/ADRDA criteria. The patients need to be fully capacitated and able to give informed consent, with a minimum MMSE-score of 17/30 (according to other AD-protocols);- Controls: patients with subjective memory complaints visiting the Alzheimer center, without diagnosis of AD or other neurodegenerative disease.
排除标准
- •- Patients with neuro-opthalmological conditions, which may interfere with the OCT and/or FAF data will be excluded (Table 2, Tewarie et al., 2012).
- •- Patients with progressive dementia, with an MMSE below 17/30 and/or incapacitated and not capable to give informed consent
- •- Patients with a narrow anterior angle of the eye and/or increased intra-ocular pressure. These patients have a contra-indication to use mydriatic agents.
研究者
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