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临床试验/NCT02497768
NCT02497768Unknown不适用

Particle Sizing of Masticated Tree Nuts - Pistachios and Brazils

King's College London1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2015年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
10
试验地点
1
主要终点
Particle size distribution of masticated nuts

研究概览

简要总结

The investigators want to understand how oral processing (chewing) of nuts affects particle size and the presence of lipid (fat) on the cut surfaces.

The main objective of the study is to:

Measure the size of nut particles that have been chewed sufficiently to be swallowed.

The secondary objective of this study is to:

Measure any changes in lipid content due to chewing and compare it to a prediction from a theoretical model.

The investigators have developed a theoretical model for determining the release of nutrients from plant foods, specifically lipid (fat) from almonds. The model has been used to calculate the amount of lipid released from chewed almonds. The model shows that only about 10% of the lipid is immediately released. The investigators require information on the particle size distribution (number of particles of each size) for other chewed nuts to calculate the amount of lipid released for other nuts. This will allow us to check the validity of our model for other foods.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Must be generally healthy
  • •Must have eaten nuts within the last month with no adverse effects

排除标准

  • •Must not be allergic to nuts of any kind
  • •Must not have any teeth missing (apart from unerupted wisdom teeth)
  • •Must not have bleeding gums
  • •Must not have had dental treatment (other than checkups) in the last 3 months
  • •Must not be currently suffering from any infectious disease that may be passed on via saliva e.g. Glandular fever, flu

研究组 & 干预措施

Chewing of nuts

Experimental

8 samples (4-5 g) of nuts (pistachios or Brazils) on two separate visit days.

干预措施: Chewing of nuts (Other)

结局指标

主要结局

Particle size distribution of masticated nuts

时间窗: At time of expectoration, up to 90 seconds after each sample ingested

Particle size distribution of masticated nuts as measured by laser diffraction and sieving.

次要结局

  • Lipid content of masticated nuts(At time of expectoration, up to 90 seconds after each sample ingested.)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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