Ultrasound-Guided Submandibular Parapharyngeal Glossopharyngeal Nerve Block for Post -Tonsillectomy Pain Relief in Adults. A Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Onset of 1st analgesic request
研究概览
简要总结
The aim of the present study is to evaluate the efficacy and safety of Ultra-sound guided submandibular parapharyngeal glossopharyngeal nerve block as regards time for first need of analgesic as a primary outcome as well as pain score, total postoperative analgesic requirement, and incidence of complications as secondary outcomes
详细描述
Tonsillectomy is one of the most frequent surgical procedures performed all over the world that has been identified as being severely painful especially in the adult population. Management of post tonsillectomy pain is of paramount importance in order to improve swallowing and enhance oral intake as well as to decrease the risk of dehydration, infection and secondary hemorrhage with a subsequent hastening of recovery.
A variety of analgesic regimens have been implemented to alleviate post-tonsillectomy pain, however; no consensus on the ideal analgesic regimen has been yet identified.
The Ultrasound (US)-guided glossopharyngeal nerve (GPN) block has been acknowledged as a feasible option for providing perioperative analgesia in tonsillectomy patients. It blocks sensory impulses from the posterior third of the tongue, palatine tonsil, and mucous membranes of the mouth and pharynx. Conventional techniques for blocking the GPN carry the risk of vascular puncture, inadvertent block of closely adjacent other cranial nerves, with increased probability of local anesthetic toxicity and even upper airway obstruction. Recently, a novel, safe, and reproducible US-guided GPN block technique has been introduced by Azman et al, which would block the GPN distally, in the tissue plane just next to the pharyngeal wall and relatively far from high risk nearby structures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients classified by the American society of Anesthesiologists ASA I and II patients
- •Scheduled for tonsillectomy procedure
排除标准
- •Patients' refusal
- •History of diabetes mellitus,
- •Cardiac, liver or renal impairment
- •Obstructive sleep apnea syndrome
- •Swallowing difficulty
- •Intake of chronic pain medications or substance abuse
- •Bleeding disorders
- •Hypersensitivity to the used medication
结局指标
主要结局
Onset of 1st analgesic request
时间窗: up to 24 hours postoperative
the time to first analgesic request will be recorded
次要结局
- Pain score(at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours postoperative)
- Postoperative rescue analgesic consumption(up to 24hours postoperative)
研究者
Mona Blough El Mourad
Assistant professor of Anesthesia, Surgical Intensive Care and Pain Medicine
Tanta University
