The Effect of Norepinephrine Versus Dopamine in Renal Transplant Recipients on Postoperative Graft Function
试验速览
- 阶段
- 2 期
- 入组人数
- 44
- 试验地点
- 1
- 主要终点
- serum creatinine
研究概览
简要总结
Renal transplantation is now recognized as a treatment of choice for patients with chronic renal failure with end-stage renal disease. Renal transplantations are associated with better quality of life, better cost/benefit ratio, and possibly longer survival. Significant changes in blood pressure are common throughout the surgical procedure for kidney transplantation. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration. All efforts are made to maintain an appropriate level of blood pressure by using an adequate intravascular volume and vasopressor administration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for a living donor kidney transplantation
排除标准
- •Patients (less than 18 years old)
- •Patients' refusal of consenting for enrolment in the study
研究组 & 干预措施
Norepinephrine
干预措施: Norepinephrine (Drug)
Dopamine
干预措施: Dopamine (Drug)
结局指标
主要结局
serum creatinine
时间窗: four hours postoperatively
postoperative
次要结局
- blood urea(four hours postoperatively)
- renal artery diameter(four hours postoperatively)
- renal artery blood flow(four hours postoperatively)
- urine output(over 24 hours)
研究者
Ahmed Abdel Kader Ahmed Mohammed Elkadi
Specialist
Assiut University
