ISRCTN77567702已完成未知

Is a multidisciplinary rehabilitation treatment more effective than monodisciplinary cognitive behavioural therapy for patients with chronic fatigue syndrome? A multicentre randomised controlled trial

The Netherlands Organisation for Health Research and Development (ZonMw) (Netherlands)0 个研究点目标入组 240 人开始时间: 2009年2月27日最近更新: 2017年7月3日

试验速览

暂无简介。

•Patients are included if they fulfil the CDC-94 criteria for CFS and score more or equal to 40 on the Checklist Individual Strength (CIS)-fatigue questionnaire. CDC-94 criteria for CFS are as follows:
•At least 6 months of persistent or recurring fatigue for which no physical explanation has been found and which:
•1. Is of new onset, that is to say it has not been lifelong
•2. Is not the result of ongoing exertion
•3. Is not substantially alleviated by rest
•4. Severely limits functioning
•In combination with four or more of the following symptoms, persistent or regularly recurring over a period of 6 months and which must not have predated the fatigue:
•5. Self-reported impairment in memory or concentration
•6. Sore throat
•7. Tender cervical lymph nodes
•8. Muscle pain
•9. Multi-joint pains
•10. Headache
•11. Unrefreshing sleep
•12. Post-exertional malaise lasting 24 hours or longer
•Other additional inclusion criteria for this study are:
•13. Patients are willing to participate in a treatment which is set up to change behaviour
•14. Aged between 18 years and 60 years, either sex
•15. Able to speak, understand and write the Dutch language

•1. Any medical condition that may explain the presence of chronic fatigue
•2. A psychotic, major or bipolar depressive disorder (but not an uncomplicated depression)
•3. Dementia
•4. Anorexia or bulimia nervosa
•5. Alcohol and/or drug abuse
•6. Severe obesity (body mass index [BMI] greater than or equal to 45)
•7. Pregnancy
•8. Not able to speak, understand or write the Dutch language
•9. Patients who had cognitive behavioural therapy (CBT) and multidisciplinary rehabilitation therapy (MRT) in the past involving CFS

发起方

The Netherlands Organisation for Health Research and Development (ZonMw) (Netherlands)