To determine the effect of Oxytocin in compared with placebo on craving; withdrawal and stress response in heroin dependents.

Vice chancellor for research Kashan University of Medical Sciences0 个研究点目标入组 50 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•Subjects must meet DSM-IV criteria for current heroin dependence ( within the past six months). Subjects must be at the beginning of treatment period and must abstain from heroin for at least three days prior to testing. patients willing to participate in the intervention- The age range of subjects must be between 20 to 60 years old. Subjects must be literate.
•Exclusion Criteria :
•Women who are pregnant, nursing or of childbearing potential and positive of pregnancy test. Subjects with evidence of or a history of significant hematological, endocrine, cardiovascular, pulmonary, renal, drug allergy or neurological disease including diabetes, as these conditions may affect physiological/subjective responses. Subjects with Addison's disease, Cushing's disease or other diseases of the adrenal cortex likely to affect hormonal/neuroendocrine status. Subjects with current major depressive disorder, bipolar or post-traumatic stress disorder as these disorders are associated with characteristic changes in stress response. Subjects receiving synthetic glucocorticoid therapy, any exogenous steroid therapy within one month of test session.
•Subjects taking any psychotropic medications, including SSRI's or other antidepressants, opiates or opiate antagonists as these medicines may affect the test response. Subjects with any acute illness or fever.
•- positive urine tests indicating abuse of any abuse or stimulant.

发起方

Vice chancellor for research Kashan University of Medical Sciences