CTRI/2024/03/064710尚未招募3 期
Comparing the effects of dexmedetomidine versus morphine as adjuvant to 0.5% levobupivacaine for spinal anaesthesia in lower abdominal surgeries
Vinayaka Missions Kirupananda Variyar Medical College and Hospitals1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年4月1日最近更新:
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The time for first rescue analgesia after the
研究概览
简要总结
Comparing between dexmedetomidine 5 micrograms and morphine 100 micrograms as adjuvant to 0.5% levobupivacaine 3 millilitre for spinal anaesthesia in lower abdominal surgeries.
Comparing the duration of sensory blockade and motor blockade after spinal anaesthesia while using either dexmedetomidine or morphine as adjuvant with levobupivacaine and also how much time prolonged for administering the first rescue analgesic in the post operative period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I and
- •Age between 18 to 60 years.
- •3.Elective lower abdominal surgeries.
- •Patient giving valid informed consent.
排除标准
- •Patient refusal
- •Age less than 18 years and more than 60 years
- •ASA grade 3 and 4
- •Patients posted for emergency surgeries
- •Patient with local infection at puncturing site
- •Patients with ischaemic and rheumatic heart disease
- •Patients with coagulation defects and patients on anticoagulants
- •Patients allergic to local anesthetic drugs.
- •Patients with neuromuscular disorders.
结局指标
主要结局
The time for first rescue analgesia after the
时间窗: 24 hours
spinal anaesthesia will be prolonged.
时间窗: 24 hours
次要结局
- Total dose of rescue analgesia required in 24 h(post-operatively will be reduced.)
研究者
Dr R Brindha
Vinayaka Missions Kirupananda Variyar Medical College and Hospitals
研究点 (1)
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