Cognitive Bias Modification Training in Adolescents Who Have Experienced Adversity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Attention biases for threatening stimuli
研究概览
简要总结
Adolescents who have experienced adversity (childhood maltreatment and other forms of broader victimisation experiences) will be randomly allocated to receive a 5-session cognitive bias modification training (with attention and interpretation bias modification modules) or a control condition. Outcome measures include measures of cognitive biases and symptoms of psychopathology; in addition, in a subset of adolescents, brain activity data will be acquired. All adolescents will complete a feedback form, upon which acceptability of the intervention will be assessed.
详细描述
Up to 80 adolescents aged 12-18 years who have experienced adversity (childhood maltreatment and other forms of broader victimisation experiences) from India and Nepal will be randomly allocated to receive a 5-session cognitive bias modification training (with attention and interpretation bias modification modules) or a control condition over a 2-week period.
Pre and post-assessment measures include measures of attention and interpretation biases and symptoms of internalising and externalising psychopathology. In addition, in a subset of adolescents, brain activity data acquired using EEG will be acquired either during resting or viewing emotional face stimuli. Data from these measures will be used to generate effect sizes of changes for each group as well as being used in a limited number of significance-testing analysis. All adolescents will complete a feedback form, upon which acceptability of the intervention will be assessed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
Participants are told that they will be allocated to one of two intervention conditions, one which may be more effective than the other in challenging negative thought patterns. Outcome assessors are blind to the status of the participant.
入排标准
- 年龄范围
- 12 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adolescents aged 12-18 years
- •Adolescents who have experienced adversity (abuse, neglect) or broader victimisation experiences (conventional crime)
排除标准
- •Adolescents who have difficulty reading or understanding what is being read to them
- •Adolescents who are currently at-risk for self-harm
- •Adolescents who are currently experiencing psychotic symptoms
- •Adolescents who are currently experiencing high-level trauma symptoms
结局指标
主要结局
Attention biases for threatening stimuli
时间窗: Immediately after the intervention (post-intervention)
The investigators will use an experimental measure (a visual search task) that uses reaction times (RTs) to different experimental conditions to index the degree to which attention is captured by a threatening over a non-threatening stimulus.
Interpretation biases for threatening explanations
时间窗: Immediately after the intervention (post-intervention)
The investigators will use an experimental measure (an ambiguous scenarios task) that uses ratings to different experimental trials to index the degree to which individuals endorse threatening over benign interpretations
次要结局
- Symptoms of emotional, behavioural and social problems(Immediately after the intervention (post-intervention))
- Acceptability of intervention(Immediately after the intervention (post-intervention))
- Event related potentials to emotional face presentations during Electroencephalogram (EEG) experiment(Immediately after the intervention (post-intervention))
研究者
Jennifer Lau
Principal Investigator
Institute of Psychiatry, London