A comparative study on combination therapy of Hydrocortisone, Vitamin C and Thiamine to Hydrocortisone alone in Septic shock patients - NI

Dasari Sai Divya0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年7月22日

试验速览

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•(1) Patients in septic shock with vasopressor requirement : a continuous infusion of epinephrine, vasopressin, nor epinephrine, dopamine or other vasopressor agent at any dose required to maintain a mean arterial pressure of at least 65 mm hg despite intravenous crystalloid resuscitation of at least 30 ml/kg
•(2) Suspected or confirmed infection as evidenced by the ordering of blood and urine cultures and the administration of at least one antimicrobial agent
•(3) Patients who are candidates for ICU admission

•(1) Shock due to other causes
•(2) Limitations of care (defined as refusal of cardiovascular and respiratory support modes) including do not intubate status
•(3) known allergy or known contraindication to Vitamin C , Thiamine , or corticosteroids
•(4) Chronic illness / disease that, in opinion of the site investigator , has an expected life span of less than 30 days unrelated to current sepsis diagnosis ( example: stage IV malignancy and neurodegenerative disease )
•(5) Pregnancy or known active breast feeding

发起方

Dasari Sai Divya