A Comparative Study of ID Fellow-based Pre-authorization VS. Pharmacist-based Pre-authorization in Reducing Antibiotic Consumptions and Hospital Expenditures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 984
- 试验地点
- 1
- 主要终点
- Defined Daily Dose (DDD) of antibiotics
研究概览
简要总结
We will conduct a cluster randomized controlled trial to compare two antibiotic pre-authorization strategies (Fellow-based vs. Pharmacist-based). We believe that amount and duration of antibiotic consumption would be lower in the pharmacist group while the clinical outcome would be equivalent between two groups.
详细描述
Study design: A cluster randomized controlled trial Settings: 6 general medical wards at Siriraj Hospital, Bangkok, Thailand
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized patients
- •Received at least one dose of controlled antibiotics (Piperacillin/Tazobactam, Imipenem/Cilastatin, Meropenem or Doripenem)
- •Each patient may be enrolled more than once, if he/she receives the controlled antibiotic for a new episode of infection (at least 48 hour apart)
排除标准
- •Died prior to receive the controlled antibiotic
研究组 & 干预措施
Fellow arm
Patients in this arm will receive the ID fellow-based antibiotic pre-authorization intervention.
干预措施: ID fellow-based antibiotic pre-authorization (Procedure)
Pharmacist arm
Patients in this arm will receive the pharmacist-based antibiotic pre-authorization intervention.
干预措施: Pharmacist-based antibiotic pre-authorization (Procedure)
结局指标
主要结局
Defined Daily Dose (DDD) of antibiotics
时间窗: Participants will be followed for the total duration of antibiotic therapy for that given infection, an expected average of 2 weeks
DDD of antibiotic use for that given infection (all antibiotics and controlled antibiotics)
次要结局
- Total duration of antibiotic use(Participants will be followed for the total duration of antibiotic therapy for that given infection, an expected average of 2 weeks)
研究者
Pinyo Rattanaumpawan
Asssitant Professor
Siriraj Hospital