Exercise-snacks: an Effective Strategy to Break Sitting Time and Improve Cardiometbaolic Health in Sedentary Overweight Office Workers
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 23
- 试验地点
- 2
- 主要终点
- Changes in aerobic fitness
研究概览
简要总结
The main objective is to measure the effects of intense brief exercise program in the workplace of administrative staff on the cardio-metabolic health
详细描述
Backgrounds: Very short (< 1 minute) and intense exercises, entitled "exercise-snacks", have been reported to be effective 1) in improving physical fitness over 6 weeks and 2) in improving vascular function and lowering blood glucose levels over one day. These studies were all carried out in the laboratory. The question therefore arises as to whether these acute vascular and metabolic benefits, as well as those on physical fitness, are sustainable over time following a chronic "exercise-snacks" program applicable in the professional environment to sedentary, overweight people.
Aims of this project is therefore to measure the effects of an "exercise-snacks" type physical activity program in the workplace of administrative staff on the cardio-metabolic health and sedentary behaviour of staff.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •administrative staff,
- •age between 30 and 60,
- •body mass index ≥25kg/m²,
- •sedentary time ≥7h/day,
- •minimum 3 working days on site,
- •no known cardiovascular or metabolic pathology, social security affiliation or benefit,
- •ability and willingness to give free, written and informed consent.
排除标准
- •pregnant or breast-feeding women,
- •anti-hypertensive treatment, beta-blockers and anti-diabetics,
- •known contraindications to physical activity (articular, cardiac or other),
- •exercise-induced asthma,
- •lack of motivation of subjects posing problems of compliance and adherence to the exercise program,
- •participation in a study in the preceding 3 months, ongoing participation in a clinical trial.
结局指标
主要结局
Changes in aerobic fitness
时间窗: at inclusion, at the end of the 4-weeks program and 1 month following the end of the program
Aerobic fitness will be assessed via the Chester step test's prediction of VO2max
次要结局
- Changes in carotid-femoral pulse wave velocity(at inclusion, at the end of the 4-weeks program)
- Changes in blood pressure(at inclusion, at the end of the 4-weeks program and 1 month following the end of the program)
- Intensity of exercise-snacks(during the 4-weeks program)
- Changes in peak shear rate of superficial femoral artery(at inclusion, at the end of the 4-weeks program)
- Changes in mean amplitude of glycemic excursions(one week before the beginning of the program and the first week of the program and the 2 lastest weeks of the program)
- Changes in heart rate(between the beginning and end of the 4-week exercise program and 4 weeks after the program.)
- Adherence of staff in the experimental group by analyzing accelerometric data.(during the 4-weeks program)
- Changes in carotid compliance(at inclusion, at the end of the 4-weeks program)
- Changes in lean mass(between the start and end of the 4-week exercise program and 4 weeks after the program)
- Change in physical activity behaviour at work of staff(between the start and end of the 4-week exercise program.)
- Changes in flow mediated dilation of superficial femoral artery(at inclusion, at the end of the 4-weeks program)
- Changes in nitrate mediated dilation of superficial femoral artery(at inclusion, at the end of the 4-weeks program)
- Changes in superficial femoral artery compliance(at inclusion, at the end of the 4-weeks program)
- Changes in post-occlusive skin perfusion(at inclusion, at the end of the 4-weeks program)
- Changes in level of habitual physical activity(between the start and end of the 4-week exercise program and 4 weeks after the program)
- Changes in rating of perceived exertion(between the start and end of the 4-week exercise program and 4 weeks after the program)
- Changes in carotid intima-thickness(at inclusion, at the end of the 4-weeks program)
- Changes in fat mass(between the start and end of the 4-week exercise program and 4 weeks after the program)