Evaluation of Horizontal Alveolar Ridge Augmentation Using Pericardial Membrane Versus Titanium Mesh" Histological and Clinical Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Histological
研究概览
简要总结
Randomized clinical trial study ,The purpose of this study To evaluate the potential application of resorbable pericardium to augment localized alveolar ridge defects in esthetic zone, from histological, radiographical and clinical aspects in comparison with titanium mish for the subsequent placement of dental implants Reconstruction of alveolar bone defect can be achieved through many regenerative surgical procedures including guided bone regeneration (GBR).Tenting of the periosteum using a cortical bone block maintains space and minimizes resorption of the particulate graft volume
详细描述
Randomized clinical trial study ,The purpose of this study To evaluate the potential application of resorbable pericardium to augment localized alveolar ridge defects in esthetic zone, from histological, radiographical and clinical aspects in comparison with titanium mish for the subsequent placement of dental implants Reconstruction of alveolar bone defect can be achieved through many regenerative surgical .
Patient selection:
20 patients will be selected from the outpatient clinic of the department of, Oral medicine and Periodontology, Faculty of Dentistry, Ain Shams University.
Patient grouping and treatment protocol The purpose of this study is to evaluate the results of alveolar ridge augmentation using two types of guided membranes.
Patients will be randomly divided into two groups according to the type of membrane will used in alveolar ridge augmentation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult patients of both sexes. Healthy adult patients; all patients were free from any systemic diseases as evidenced Burkitt's Oral Medicine health history questionnaire Age from 20-50 years old. partially edentulous area in upper arch esthetic zone (incisors to premolar area). Residual bone width ≤4 mm and minimum alveolar vertical dimension measured ≥8 mm from the alveolar crest to the roof of the nasal cavity or maxillary sinus, (H.2.e) (Cologne Classification 2013).
排除标准
- •Subjects with any systemic disease or conditions according to health questionnaire assessment modified from oral medicine .
- •uncontrolledly diabetic HBAc1 more than 8 history of base phosphonate medication history of radiotherapy medication Active periodontal disease. Smokers more than 5 cigarettes per day Pregnant and breastfeeding females . Mentally retarded patients. Vulnerable groups (prisoners, mentally disabled, and decision impaired individuals).
结局指标
主要结局
Histological
时间窗: 4 months
histomorphometric evaluation of the grafted boneThe area fraction (AF) of newly formed bone was measured automatically. The area fraction represents the percentage of the newly formed bone trabeculae to the total area of the microscopic field. The mean area fraction (MAF) for each case was calculated. Estimation of osteocytes count in each microscopic field, viable osteocytes within their lacunae in the newly formed bone
次要结局
- clinical(4 months)
研究者
Ahmed Wafaa Abaza
general practitioner
Ain Shams University