CTRI/2024/04/066155已完成Unknown
A comparative study on efficacy of intralesional methotrexate vs intralesional triamcinolone acetonide in chronic plaque psoriasis
Sampath V1 个研究点 分布在 1 个国家目标入组 84 人开始时间: 2024年5月7日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 已完成
- 发起方
- 入组人数
- 84
- 试验地点
- 1
- 主要终点
- 1. To compare the efficacy of intralesional Methotrexate (MTX) and Triamcinolone in the treatment of Chronic plaque psoriasis both clinically and using Dermoscopy.
研究概览
简要总结
In Chronic Plaque Psoriasis, Intralesional therapy can be used, as it delivers a higher concentration of the medicine at the site of injection while avoiding the recognized side effects of systemic therapy. The drawback of Topical treatment is inadequate drug penetration. This drawback is nullified by intralesional therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients with clinical features of chronic Plaque psoriasis with less than 5 Plaques 2) Patients who have given consent for the study and are willing to come for regular follow up at the psoriasis clinic.
- •Patients who had not been on any systemic and topical anti psoriatic medications for at least the past 2 months will be enrolled.
排除标准
- •Patients with unstable psoriasis 2) Pregnant and Lactating Women 3) Patients of Psoriasis vulgaris with history of Hypersensitivity to MTX or Triamcinolone.
- •Patients with bleeding disorders and on anti-coagulant therapy.
结局指标
主要结局
1. To compare the efficacy of intralesional Methotrexate (MTX) and Triamcinolone in the treatment of Chronic plaque psoriasis both clinically and using Dermoscopy.
时间窗: 6 weeks,12 weeks,24 weeks
次要结局
- 2. To compare the common side effects of Intralesional Methotrexate and Triamcinolone Acetonide in Chronic Plaques Psoriasis.(6 weeks,12 weeks,24 weeks)
研究者
Sampath V
Madras medical college
研究点 (1)
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