Personalized Blood Flow Restriction for Anterior Cruciate Ligament Rehabilitation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Knee Varus
研究概览
简要总结
This is a cross-sectional study on the use of personalized blood flow restriction during rehabilitation exercises and its effects on biomechanics on people who have had an anterior cruciate ligament reconstruction and healthy controls
详细描述
Rehabilitation after surgical reconstruction of the anterior cruciate ligament (ACL) aims to reestablish the function of the knee. However, regaining previous levels of strength is challenging, with long-term muscle weakness frequently reported and thought to play a key role in the increased risk of knee osteoarthritis for individuals with a history of ACL damage. Effectively building muscle strength requires exercises with high resistance loads, however the joint stress and risk of further injury makes these types of activities inappropriate and unsafe for those rehabilitating after ACL reconstruction surgery and other injuries. Personalized blood flow restriction (BFR) training is a technique where the blood flow to the muscles being exercised is controlled by a pressure cuff to a predefined level, and has been shown to increase strength while exercising with significantly lower loads. Early results have been promising, however the effects of BFR on the biomechanics of the exercise as well as the acceptability in the ACL reconstruction population have not been explored. In this application, we propose a cross-sectional study designed to test the acceptability of BFR training for those undergoing rehabilitation from ACL reconstruction surgery and healthy controls during free standing exercises. We will also investigate the biomechanical effects of this rehabilitation technique. This application is part of a larger program of musculoskeletal research in this area being developed by the team. The results from the proposed project will inform the design of a clinical trial of personalized BFR after ACL reconstruction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Any other orthopaedic, neurological, or other condition within the last 12 months that would affect ability to carry out the required exercises
- •Any medical conditions that may affect circulation including, but not limited to, deep vein thrombosis, high blood pressure, and cardiac disease
结局指标
主要结局
Knee Varus
时间窗: 6 minutes
Maximum difference in varus motion of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Hip Internal Rotation Moment
时间窗: 6 minutes
Maximum difference in internal rotation moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Hip Adduction
时间窗: 6 minutes
Maximum difference in adduction motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Hip Internal Rotation
时间窗: 6 minutes
Maximum difference in internal rotation motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Hip Flexion
时间窗: 6 minutes
Maximum difference in flexion motion of hip while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Knee Flexion
时间窗: 6 minutes
Maximum difference in flexion motion of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Knee Internal Rotation
时间窗: 6 minutes
Maximum difference in internal rotation of knee while performing exercise between baseline and blood flow restriction condition. Measured in degrees
Knee Internal Rotation Moment
时间窗: 6 minutes
Maximum difference in internal rotation moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Knee Adduction Moment
时间窗: 6 minutes
Maximum difference in adduction moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Hip Extension Moment
时间窗: 6 minutes
Maximum difference in extension moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram.
Knee Extension Moment
时间窗: 6 minutes
Maximum difference in extension moment of knee while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
Hip Adduction Moment
时间窗: 6 minutes
Maximum difference in adduction moment of hip while performing exercise between baseline and blood flow restriction condition. Measured in Newton meters per kilogram
次要结局
- Exercise Difficulty Score(6 minutes)
- Exercise Discomfort Score(6 minutes)
研究者
Scott Telfer, EngD
Assistant Professor: School of Medicine
University of Washington