Evaluation of hemodynamic effects of cascade hemofiltration in septic shock

Gambro Industries, Clinical Affairs Department (France)0 个研究点目标入组 60 人开始时间: 2008年2月1日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Patient with a septic shock diagnosed by the medical staff team
•2. Patient mechanically ventilated and treated by high doses of catecholamines after adequate fluid administration (superior or equal to 1.0 mg/h of norepinephrine or epinephrine) for more than 120 minutes and <24h
•Note: Patients with renal failure (treated or not) can be included

•1. Age (years) <18 or >85
•2. Weight >120 kg
•3. Thrombocytopenia 50< G/l or Neutrophils <0.5 Giga/l
•4. Contra indication to heparin anticoagulation
•5. Patient requiring catecholamines (epinephrine or norepinephrine superior or equal to 1 mg/h) for >24h
•6. Patient admitted to the Intensive Care Unit (ICU) superior or equal to 7 days before the inclusion criteria
•7. Patient with intercurrent disease limiting his/her self-sufficiency (need of help before septic shock)
•8. Inclusion (<28 days) in another study interfering with the goals of the current investigation
•9. Pregnancy and patient under guardianship
•10. Immune compromised patients (e.g., being treated for cancer, treated by immunosuppressors or steroids, AIDS)

发起方

Gambro Industries, Clinical Affairs Department (France)