Effects of Expiratory Muscle Training on Cough Efficacy in Children and Adolescents With Cystic Fibrosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Cough capacity
研究概览
简要总结
Cystic fibrosis (CF) is an autosomal recessive genetic disease characterized by recurrent airway infections, affecting many systems including lung, pancreas and sweat glands. Cough is an important defense mechanism for clearing the secretions that increase in respiratory diseases. There have been studies investigating the effect of expiratory muscle training on disease groups such as chronic obstructive pulmonary disease, multiple sclerosis, parkinson's disease, and the elderly and healthy individuals. Studies that evaluating effects of expiratory muscle training in cystic fibrosis are limited in the literature. The aim of this study was to evaluate the effect of cough strength in children and adolescents with CF and the effect of expiratory muscle training program on cough strength, exercise capacity, respiratory muscle strength and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 8 Years 至 18 Years(Child, Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Diagnosed with cystic fibrosis
- •8-18 years
- •Clinically stable during last six weeks
排除标准
- •hemoptysis
- •low saturation (SpO2<90%)
- •acute lower respiratory tract infection
- •cardiac problems (heart failure, arrhythmia, cardiomyopathy, etc.)
- •cognitive problems
- •pneumothorax
结局指标
主要结局
Cough capacity
时间窗: 6 weeks
peak expiratory flow meter
次要结局
- Respiratory muscle strength(every two weeks)
- Exercise capacity(6 weeks)
研究者
Cigdem Emirza
Physiotherapist
Istanbul University
