JPRN-jRCT2080221095未知1 期
A Phase I, Open-Label Study to Assess the Safety, Tolerability and Pharmacokinetics of Ascending Doses of MEDI-575 in Patients With Advanced Solid Malignancies
试验速览
- 阶段
- 1 期
- 发起方
- AstraZeneca
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-Randomized Endpoint Classification: Safety Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- All
入选标准
- •Having advanced solid malignancy for which no curative or standard therapies exist
- •- Karnofsky performance status of 60 or more
- •- Patients must have histological confirmed diagnosis of HCC with no standard therapy available (for only expansion part)
排除标准
- •- Inadequate bone marrow reserve or organ function
- •- Major surgery within 4 weeks or minor surgery within 2 weeks prior to receipt of MEDI-575. Patients must have no unhealed wounds or unhealed fractures
- •- History of allergy or reaction to any component of the MEDI-575 and/or monoclonal antibody
研究者
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