临床试验/NCT07288762

NCT07288762尚未招募不适用

Gonadal Function in Boys With Transfusion Depandant Beta Thalassemia

Sohag University0 个研究点目标入组 80 人开始时间: 2025年12月7日最近更新: 2025年12月17日

试验速览

阶段: 不适用
状态: 尚未招募
发起方: Sohag University
入组人数: 80
主要终点: gonadal function in transfusion depandant beta thalassemia

研究概览研究设计入排标准结局指标研究者记录与标识符相似试验

研究概览

简要总结

Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .

详细描述

detection of any abnormalities in pituitary gland hormones ( FSH , LH , serum prolactin ) gonadal hormones ( serum testesterone , antimullerian hormone , INSL3 , inhibin B hormone )

研究设计

研究类型: Observational
观察模型: Case Control
时间视角: Cross Sectional

入排标准

年龄范围: 10 Years 至 18 Years（Child, Adult）
性别: Male
接受健康志愿者: 是

入选标准

•transfusion depandant beta thalassemia
•age 10 to 18 year old age

排除标准

•age below 10 year old age or above 18 year old age
•associated with another disease

结局指标

主要结局

gonadal function in transfusion depandant beta thalassemia

时间窗: through study completion, an average of 1 year

gonadal function assessment by Inhibin B hormone, INSL3 , serum testesterone that analysed in patient with age 10 - 18 year old for early detection of any abnormality

次要结局

未报告次要终点

研究者

发起方

Sohag University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Hager Saadeldin Mohamed

pediatric resident

Sohag University

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