Retrospective Analysis of Video-EEG Findings and Clinical Characteristics in Adult Patients With Psychogenic Nonepileptic Seizures
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Semiological subtype of PNES events
研究概览
简要总结
This completed retrospective observational study evaluated adult patients diagnosed with psychogenic nonepileptic seizures (PNES) who underwent video-EEG monitoring. Video-EEG records and clinical data of 50 adult patients were reviewed to describe semiological, electroclinical, and demographic characteristics of PNES. The study aimed to improve the understanding of video-EEG findings in PNES and to support accurate diagnosis in clinical practice.
详细描述
Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on EEG. Video-EEG monitoring is considered the reference standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical files of 50 adult patients with PNES were reviewed after completion of clinical care. Demographic data, clinical presentation, and video-EEG characteristics were analyzed descriptively. No intervention was assigned as part of the study. The purpose was to characterize the video-EEG and clinical profile of adult PNES patients evaluated in routine practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years and older
- •Diagnosis of psychogenic nonepileptic seizures based on video-EEG evaluation
- •Availability of complete video-EEG recordings and relevant clinical records for review
排除标准
- •Patients younger than 18 years
- •Inadequate or incomplete video-EEG data
- •Patients with insufficient clinical documentation for retrospective evaluation
结局指标
主要结局
Semiological subtype of PNES events
时间窗: Baseline retrospective chart and video-EEG review
Classification of PNES events recorded during video-EEG monitoring into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features.
次要结局
- Presence/absence of some events during PNES events(Baseline)