Distal Tibia Sarcoma Treatment Using Allograft Arthrodesis of the Ankle
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- principal diagnosis of the patients that wen trough ankle after resection of a primary malignant tumor of the distal tibia
研究概览
简要总结
The study show the clinical results of limb salvage for primary malignant bone tumor of the distal tibia using block excision of the tumor and reconstruction with allograft arthrodesis with different methods of fixation (plates or intramedullary nail system)
详细描述
It is well known that before the 1980's the usual treatment for the sarcomas of the distal tibia was amputation (1). Currently, however, after the improvement of the chemotherapy treatments, potential reconstructions of the area in well studied patients are possible, and for that we have a wide range: auto graft, allograft and prosthetic reconstructions (2, 3)
Is important to know that osteosarcoma still meant the principal diagnosis, followed by the Ewing sarcoma and synovial sarcoma, but their malignant potency is lower than when they are present in the rest of the body (4, 5, and 6)
The purpose of this study is to recollect the patients' data followed from different institutions and countries that have the criteria for their inclusion in the study (primary malignant bone tumor of the distal tibia that underwent block excision of the tumor and reconstruction with allograft arthrodesis from the patient management for any of the multidisciplinary sarcoma team including in this study).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients with histopathologyc diagnosis of a primary malignant bone tumor at the distal tibia that went through a tumor resection and received reconstruction with allograft as first surgical treatment
排除标准
- •none histopatologic proved diagnosis
- •patients that received other kind of surgical treatment
结局指标
主要结局
principal diagnosis of the patients that wen trough ankle after resection of a primary malignant tumor of the distal tibia
时间窗: 1 month
osteosarcoma: 5 patientas (2 females of 18 and 15 years old and 3 males of 19, 24 and 16 years old) telangiectasic osteosarcoma (1 female of 21 years old) Ewing sarcoma (1 male of 33 years old)
次要结局
- MSTS SCORE(5 month to 10 years follow up)
- mobility(5 month to 10 years follow up)
- mortality(5 months to 10 years follow up)
研究者
Patricia Bonilla
Orthopedic Oncologist MD
Hospital del Niño "Dr. José Renán Esquivel"