To compare the outcome of therapeutic penetrating keratoplasty for fungal keratitis with late vs immediate postoperative addition of topical corticosteroids.

V Prasad Eye Institute0 个研究点目标入组 0 人开始时间: 待定最近更新: 2022年6月27日

试验速览

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•1.Cases with microbiologically confirmed fungal keratitis undergoing therapeutic keratoplasty for worsening of infection.
•2.Size of infiltrate less or equal to 10 mm.
•3.Intraoperative no evidence of residual infection
•4.Immediate Post operative anterior chamber formed and no clinical evidence of infection
•5.Use of MK medium corneal tissue of any grade with or with out intact epithelium
•6.Intraoperative Preserved lens
•7.Ready to give consent
•8.Consent for regular follow-up
•9.More than 18 years
•10.Surgery performed by surgeons with experience of performing more than 20 TPK.

•1.Any evidence of intraop or clinical post-operative infection
•2.Size of infiltrate > 10 mm
•3.Not willing to come for regular follow-up or admission or giving consent
•4.Disorganized anterior chamber
•5.Posterior segment involvement as confirmed on Echoes in the posterior segment on B scan
•6.Intraoperative presence of retero-iris and lens exudates.
•7.Presence if corneal perforation before the surgery
•8.Presence of uncontrolled diabetes or any other cause of decreased imununity.

发起方

V Prasad Eye Institute