Evaluation of Malnutrition in Patients Undergoing Major Abdominal Surgery Using GLIM Criteria and Comparing CT and BIA for Muscle Mass Measurement
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 260
- 主要终点
- overall complications
研究概览
简要总结
Evaluation of malnutrition with the help of the GLIM criteria. Muscle mass measurement, as recommended in the GLIM criteria was done with the help of abdominal CT scan and BIA. Both methods were compared and their association to the clinical outcome was assessed.
详细描述
We retrospectively analysed 260 patients undergoing major abdominal surgery between January 2017 and December 2019. Patients were prospectively screened and assessed for malnutrition with Nutritional Risk Score (NRS) and Subjective Global assessment (SGA). Body composition was analysed with CT scan and BIA within 30 days before surgery. GLIM criteria were retrospectively determined referring to the Fat free Mass from BIA (FFMBIA) and Muscle Mass from axial CT scan at lumbar level 3 (MMCT). The prevalence of GLIM - malnutrition according to BIA and CT was evaluated. Multivariate logistic regression analysis was used to determine association between malnutrition and outcome parameters. ROC-curves specified sensitivity and specificity of the different tools and areas under the curve were calculated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age above 18 years
- •BIA and CT scan was available within 31 days before surgery
- •patients undergoing major abdominal surgery for gastrointestinal cancer
排除标准
- •patients who were not able to agree to the participation
- •missing assessment of the nutritional status
- •leck of quality of the CT scan
结局指标
主要结局
overall complications
时间窗: 31 days POD
all complications perioperatively including surgical side infections, anastomic leakage, sepsis
次要结局
未报告次要终点
研究者
Maria Wobith
Principle Investigator
Klinikum St. Georg gGmbH