Comparison of Functionality, Physical Activity, Cardiac and Respiratory Parameters Between Patients With Mood Disorders and Healthy Controls
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 65
- 试验地点
- 1
- 主要终点
- 3 minute step test (Assessment of exercise capacity)
研究概览
简要总结
The importance of cardiorespiratory impact in mental diseases is generally emphasized in studies, but it is noteworthy that cardiorespiratory affects in mood disorders have not been sufficiently investigated. This study aims to compare individuals with mood disorders and healthy people in terms of exercise capacity, functionality, respiratory muscle strength, respiratory functions, dyspnea and physical activity level.
详细描述
The cross-sectional study was carried out with 30 patients with diagnosis of mood disorder who applied to the Hatay Mustafa Kemal University Research and Practice Hospital, Mental Health and Diseases clinic, and 35 healthy individuals whose age, gender were matched. Clinical characteristics, exercise capacity (6-minute walking test, 6MWT; 3-minute Step test, 3MST), functionality (vertical jump test, functional reach test), respiratory parameters (Respiratory muscle strength, pulmonary function test), dyspnea (Modified Medical Research Council, MMRC scale), physical activity level (short form international physical activity questionnaire, IPAQ) was evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy volunteers who had undergone a general physical examination in the past 6 month
- •reported being free of significant cardiovascular, respiratory, neuromuscular, and endocrine disorders that preclude safe participation
排除标准
- •Individuals with significant cardiovascular, neuromuscular and endocrine disorders,
- •pregnant women,
- •people under 18 years old
- •disabled individuals.
结局指标
主要结局
3 minute step test (Assessment of exercise capacity)
时间窗: Baseline
3 minute step test, In this test, the person ascends and descends the 30.5 cm step with the rhythm of the metronome set at 96 beats/min for 3 minutes.
Six minute walking test (Evaluation of exercise capacity)
时间窗: Baseline
Six minute walking test, The patients were allowed to rest for at least 30 minutes pre-starting the test, which was performed according to ATS criteria. The participants were asked to walk as fast as they can without running in a 30-meter straight corridor for 6 minutes at their own walking pace
次要结局
- Physical activity(Baseline)
- forced expiratory volume in the first second (FEV1) (Pulmonary function)(Baseline)
- Vertical jump test (Functionality 1)(in a time through the study completion, an average of 5 minutes)
- The Functional Reaching Test (Functionality 2)(Baseline)
- Forced vital capacity (FVC) (Pulmonary function)(Baseline)
- ratio of forced expiratory volume in the first second to forced vital capacity (FEV1/FVC)(Baseline)
- peak expiratory flow rate (PEF)(Baseline)
- forced mid-expiratory flow rate (FEF25-75%)(Baseline)
- Respiratory muscle strenght(Baseline)
研究者
Irem Hüzmeli
assistant professor
Mustafa Kemal University