"Autogenous Tooth Bone Graft for Alveolar Socket Preservation: A CBCT-Based Clinical Trial With 6-Month Follow-Up"
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- "Alveolar Bone Height, Width, and Density Preservation with Autogenous Tooth Bone Graft"
研究概览
简要总结
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction. Before being inserted into the socket, the graft is made from the patient's own extracted tooth and ground into a particle. Twenty Yemeni patients who needed their teeth extracted are included in the trial, and they will be followed up with clinical and radiographic procedures using cone-beam computed tomography (CBCT) for six months. The primary objective is to ascertain whether the autogenous dental bone graft can preserve the height, width, and density of alveolar bone, offering a secure, affordable, and biocompatible substitute for traditional grafting materials.
详细描述
This interventional clinical study investigates the role of autogenous tooth bone graft in alveolar socket preservation after surgical tooth extraction. The extracted tooth is cleaned, dried, processed into particulate graft material manually using bone crusher, and disinfect and treated using (NaOH) and (Na CL). The graft particles are immediately placed into the fresh extraction socket and sutured. Twenty Yemeni patients requiring impacted lower third molar and upper canine teeth surgical extractions will be included. The healing process will be evaluated both clinically and radiographically over a 6-month period. Cone-beam computed tomography (CBCT) scans will be used to assess bone density and alveolar ridge dimensions before extraction and at six months' post-intervention. The study aims to determine whether autogenous tooth bone grafts can effectively reduce post-extraction alveolar bone resorption and maintain ridge dimensions, supporting their potential use as an autologous, biocompatible, and economically feasible graft material for clinical socket preservation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Absence of systemic diseases.
- •Very good to accepted oral hygiene.
- •Patients with impacted teeth requiring extraction.
- •Patients between the ages of 16 and
- •No history of smoking.
- •No history of any other drug use.
- •Patients who were cooperative, motivated, to attend the follow-up and maintenance visits.
排除标准
- •Systemic conditions or pharmacological therapies that could be an absolute contraindication for the intervention (such as un controlled diabetics, immunocompromised states, or treatment with oral or parenteral bisphosphonates).
- •Poor oral hygiene.
- •Acute exacerbation of chronic infection like pain or swelling.
- •Pregnant women, children, elderly (>60 years), physically and mentally challenged, terminally and seriously ill.
- •Hight Smoking tendency.
- •Patients who refused to participate in the trial.
- •Uncooperative Patients who won't be able to maintain the follow up visits
研究组 & 干预措施
Autogenous Tooth Bone Graft Intervention Group
"In this arm of the study, participants will receive an autogenous tooth bone graft for alveolar socket preservation following surgical tooth extraction. The intervention involves the extraction of the patient's own tooth, which will be processed and used as a bone graft. This graft will be placed into the empty socket immediately after the extraction. The purpose of this intervention is to prevent bone resorption, promote natural healing, and support bone regeneration within the extraction site. CBCT scans will be performed before extraction to measure baseline bone dimensions and will be repeated 6 months post-intervention to assess the success of bone preservation in terms of height, width, and density."
干预措施: "Autogenous Tooth Bone Graft" (Biological)
结局指标
主要结局
"Alveolar Bone Height, Width, and Density Preservation with Autogenous Tooth Bone Graft"
时间窗: "Before extraction and 6 months post-intervention"
This study aims to evaluate the effectiveness of autogenous tooth bone grafts in preserving alveolar bone following tooth extraction. The study will assess changes in alveolar bone height, width, and density using Cone Beam Computed Tomography (CBCT) at two time points: before extraction (baseline) and 6 months post-grafting. The outcome measures are: Alveolar Bone Height: Measured in millimeters using CBCT at baseline and 6 months. Alveolar Bone Width: Measured in millimeters using CBCT at baseline and 6 months. Alveolar Bone Density: Measured in Hounsfield units using CBCT at both time points. The intervention involves using the patient's own extracted tooth to create a bone graft placed into the socket, promoting healing and bone regeneration. This study will determine the effectiveness of autogenous tooth bone grafts in preventing bone resorption and preserving alveolar socket structure.
次要结局
未报告次要终点
研究者
Haifaa Mohammed Al-hussini
"Principal Investigator, Haifaa Al-Hussini, BDS, MSc Candidate, Sana'a University"
Sana'a University