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临床试验/NL-OMON41353
NL-OMON41353已完成不适用

Randomized controlled trial of neurostimulation treatment for apathy in schizophrenia - Neurostimulation as a treatment of apathy with vulnerability for psychosis

niversitair Medisch Centrum Groningen0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
150

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 至 99(—)

入选标准

  • - At least 18 y.o.a.
  • - Diagnosis schizophrenia, according to DSM IV
  • - Minimum score AES (27)
  • - Written informed consent
  • Healthy subjects:
  • - At least 18 y.o.a.
  • - written informed consent

排除标准

  • -Metal implants (pacemaker, heart valves, vascular clips, eye-implants, copper containing intra-uterine devices, or non-removable piercing)
  • - Any risk of having metal particles in the eyes due to manual work without proper eye protections - Tattoos containing iron oxide (often found in red pigments)
  • - (suspected) Pregnancy
  • - Claustrophobia
  • - Refused to be informed (via the general practisioner of the patient) of structural brain abnormalities that could be detected during the experiment;TMS:
  • - Diagnosis of epilepsy, or a personal or first degree family history of epileptic seizures
  • - Medications associated with increased seizure risk
  • - Brain surgery
  • - Neurological problems in the past or at present
  • - Intracerebral implants;tDCS:
  • - Metal implants inside the skull or eye
  • - Severe scalp skin lesions;Treatment of tDCS of rTMS within the past year.;Relative contra-indications for tDCS:
  • - A history of previous seizures or predisposing factors that might increase seizure risk such as neuromodulatory medication
  • Additional exclusion criteria for healthy subjects:
  • History of psychiatric or neurological illness

研究者

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