NL-OMON41353已完成不适用
Randomized controlled trial of neurostimulation treatment for apathy in schizophrenia - Neurostimulation as a treatment of apathy with vulnerability for psychosis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •- At least 18 y.o.a.
- •- Diagnosis schizophrenia, according to DSM IV
- •- Minimum score AES (27)
- •- Written informed consent
- •Healthy subjects:
- •- At least 18 y.o.a.
- •- written informed consent
排除标准
- •-Metal implants (pacemaker, heart valves, vascular clips, eye-implants, copper containing intra-uterine devices, or non-removable piercing)
- •- Any risk of having metal particles in the eyes due to manual work without proper eye protections - Tattoos containing iron oxide (often found in red pigments)
- •- (suspected) Pregnancy
- •- Claustrophobia
- •- Refused to be informed (via the general practisioner of the patient) of structural brain abnormalities that could be detected during the experiment;TMS:
- •- Diagnosis of epilepsy, or a personal or first degree family history of epileptic seizures
- •- Medications associated with increased seizure risk
- •- Brain surgery
- •- Neurological problems in the past or at present
- •- Intracerebral implants;tDCS:
- •- Metal implants inside the skull or eye
- •- Severe scalp skin lesions;Treatment of tDCS of rTMS within the past year.;Relative contra-indications for tDCS:
- •- A history of previous seizures or predisposing factors that might increase seizure risk such as neuromodulatory medication
- •Additional exclusion criteria for healthy subjects:
- •History of psychiatric or neurological illness
研究者
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