An observational comparative study to assess the hemodynamic changes between preeclampsia patient versus healthy parturients after spinal anaesthesia during elective cesarean section

Spinal anaesthesia is generally preferred anaesthetic technique in preeclampsia patients as there are lower incidence of spinal induced hypotension and the vasopressor requirement in them . A total of 100 parturients fulfilling the inclusion criteria ( 50 preeclamptic and 50 healthy ) will be enrolled in the study after providing informed written consent . In operation theatre baseline hemodynamic variable ( systolic blood pressure ,diastolic blood pressure , mean arterial pressure , HR and SPO2 ) will be recorded . A 18G cannula will be secured and preoperative fluid equal to 10ml /kg of Ringer’s lactate will be administered to each patient over the course of 15- 20 min. Under aseptic precaution Spinal anaesthesia will be performed with 10mg hyperbaric 0.5% bupivacaine in two groups in sitting position in the L3 - L4 vertebral interspace , Each patient will be placed in supine position with a left lateral tilt of 15- 20 degree . The height of sensory block will be assessed using a pin prick test. After achieving an adequate sensory block (T6 level ) the surgery will be started . HR and BP will be recorded before performing spinal anaesthesia , at 2 min interval for 15 min after the block and then every 5 min until the end of surgery . Patient will also be assessed for hemodynamic changes , requirement of injection ephedrine , intraoperative fluid and complication if any .