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临床试验/NCT05226260
NCT05226260已完成不适用

Decreasing Antibiotic Duration for Skin and Soft Tissue Infections in Pediatric Primary Care Using Behavioral Economics Methods, A Cluster Randomized Trial

Nationwide Children's Hospital2 个研究点 分布在 1 个国家目标入组 1,634 人开始时间: 2021年11月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
1,634
试验地点
2
主要终点
Rate of short antibiotics

研究概览

简要总结

Study the efficacy of a package of behavioral economics strategies (versus an education-only control condition) in altering clinician behavior regarding antibiotic prescription duration for skin and soft tissue infection (SSTI).

详细描述

The investigators propose a prospective, cluster randomized trial of Epic order panels in the 14 Nationwide Children's Hospital (NCH) primary care clinics. Investigators have designed user-friendly Epic order panels from which providers may select guideline concordant antibiotics by simply typing in a diagnosis (cellulitis) or antibiotic name. These order panels are prepopulated with the default, short-course (guideline-concordant) antibiotic duration, saving clinicians several clicks within the electronic medical record (EMR). If a provider changes the prescribed duration from the one defaulted, a free text box will appear for them to write an acknowledgement reason (accountable justification). All 14 clinics will receive baseline education (control condition) about common infections and local and national guidelines for antibiotic choice and duration of treatment. Clinician prescribers will also be instructed about the presence of a basic order panel. The full functionality of the default [short/desired] duration order panel will only be released to intervention clinics. The order panels will be restricted in Epic to clinics randomized to the intervention. The investigators hypothesize that clinics with the intervention will have higher rates of short course antibiotics for SSTI versus control clinics.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Triple (Participant, Care Provider, Investigator)

入排标准

年龄范围
3 Months 至 99 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • diagnosis codes A46 (cellulitis), L03 (cellulitis and acute lymphangitis), J34 or L02 (abscess, furuncle), or L01 (impetigo) AND
  • those who received a prescription for an enteral antibiotic
  • patient's treated in Nationwide Children's Hospital primary care clinics

排除标准

  • Patients less than 3 months of age
  • Animal bite
  • Human bite
  • Foreign body
  • Diagnosis of hidradenitis suppurativa
  • Immunocompromising conditions (primary immune deficiency, chemotherapy, etc)

结局指标

主要结局

Rate of short antibiotics

时间窗: 12 months

Rates of long and short antibiotics will be analyzed on the clinic and provider level for both intervention and control groups

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Joshua Watson

Principal Investigator

Nationwide Children's Hospital

研究点 (2)

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