DRKS00013183Enrolling By Invitation不适用
Association between severity of mucositis, changes in different saliva parameter and the cellular wound healing potency during and after a radiation therapy in case of cancer in the head neck area - MuSWu1
Stiftungsprofessur für Kariesforschung Klinik für Zahnerhaltungskunde und Parodontologie Department f. Zahn-, Mund- u. KieferheilkundeUniversitätsklinikum Freiburg0 个研究点目标入组 50 人开始时间: 2018年4月26日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •Patients: Age of majority, informed consent, sufficient knowledge of German, tumor in the oral cavity, oropharynx, hypopharynx or larynx, planned radiation in the head, neck area according to a standardized protocol (cisplatin-based radiochemotherapy with a radiation dose of 60-70 Gy in a fractionation of 5 x 2 Gy / week)
- •Controls: Age of majority, informed consent, sufficient knowledge of German
排除标准
- •Patients: Presence of xerostomia or hyposalivation prior to radiation, prior to tumor therapy drug intake with influence on salivation, prior to tumor therapy antibiotic or antifungal drug intake (currently up to three months prior to the start of the study), failed tooth restoration at the beginning of radiation (cavitated carious lesions, insufficient fillings down to the dentin, deep and inflamed periodontal pockets), allergies to the dental materials used and the local anaesthetic, complete or partial removal of the large salivary glands as part of surgical tumour therapy, pregnancy or breastfeeding.
- •Controls: Presence of xerostomia or hyposalivation, medication with influence on salivation, intake of an antibiotic or antifungal (currently up to three months before the start of the study), dentition in need of restoration (cavitated carious lesions, insufficient fillings down to the dentin, deep and inflamed periodontal pockets), allergies to the dental materials used and the local anaesthetic, complete or partial removal of the large salivary glands, pregnancy or nursing period
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