跳至主要内容
临床试验/CTRI/2024/02/062315
CTRI/2024/02/062315尚未招募不适用

To study defined domains of cognitive functioning using computer based assessment system in patients of opioid dependence disorder

Mrinmai Pevekar1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2024年2月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
100
试验地点
1
主要终点
To assess defined cognitive domains in patients of Opioid dependence disorder

研究概览

简要总结

Participants will be recruited for the study based on inclusion and exclusion criteria. Patients will be taken from in-patient de-addiction ward and out patient  department from Department of Psychiatry, Punjab institute of Medical Science , Jalandhar. Participants will be verbally interviewed, in which the investigator will obtain a brief socio-demographic detail of the participants, followed by  detailed history of opioid and other substance use will be obtained including the current treatment details. Criteria of Opioid use disorder will be applied based on ICD-10 (International Classification of Diseases), those fulfilling the criteria will be selected for study. Participants included in the study will be then evaluated for psychiatric morbidities as it is one of the exclusion criteria using the SCAN (Schedule for clinical Assessment in Neuropsychiatry ), this will be applied by the investigator. They will be undergoing IQ assessment done by Clinical Psychologist using Ravens Progressive Matrices. Participants scoring below 90 will be excluded from the study.

Participants current stage in Opioid use disorder will be assessed with help of Clinical Opioid withdrawal scale (COWS) by the investigator.  Those scoring less than 5 will be included in the study.

Then the self-administered computer based testing of cognition will be done  using CANTAB , where the participant will be supervised by the investigator in case they have difficulty in conducting the test. Following this the scores obtained on the scales will be noted using Microsoft excel sheet and will be statistically  analyzed. Comparison based on socio-demographic and clinical parameters like dose of opioid use, duration of Opioid use will be done and results will be analyzed using appropriate statistical tests.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 59.00 Year(s)(—)
性别
All

入选标准

  • Diagnosed with Opioid dependence according to ICD-10.

排除标准

  • Those having any psychiatric comorbidities ( except substance use disorder )
  • Those currently in withdrawal.
  • Those having below average intelligence
  • Those medical illness with likely central nervous system manifestation ( e.g Stroke, SLE, Porphyrias)
  • History of significant head injury.
  • Those having physical ailments which would render it difficult or impossible to perform tests e.g. blindness, hearing impairment .

结局指标

主要结局

To assess defined cognitive domains in patients of Opioid dependence disorder

时间窗: At baseline

次要结局

  • To find association between socio-demographic variables & patterns of Opioid dependence disorder with various domains of Cognition .

研究者

发起方
Mrinmai Pevekar
申办方类型
Other [Principal Investigator]
责任方
Principal Investigator
主要研究者

Mrinmai Krishna Pevekar

Punjab Institute of Medical Sciences, Jalandhar

研究点 (1)

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