Assessment of pain relief and functional improvement following intra articular nanofat grafting in adults with temporomandibular joint internal derangement: A prospective interventional study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 17
- 试验地点
- 1
研究概览
简要总结
Temporomandibular disorders (TMD-ID) are a common cause of chronic orofacial pain and functional limitation affecting mastication and quality of life. Persistent symptoms despite conservative management necessitate evaluation of alternative therapeutic modalities.
This single-arm interventional study aims to evaluate the efficacy of intra-articular nanofat graft injection in patients clinically diagnosed with temporomandibular disorder internal derangement (TMD-ID) based on the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) Axis I.
The primary objective of the study is to assess the effectiveness of intra-articular nanofat graft injection in reducing pain and improving mandibular function in patients with TMD-ID.
A total of 9 participants (17 temporomandibular joints) will be included in the study. Following baseline clinical assessment, eligible patients will receive intra-articular nanofat graft injection under aseptic conditions.
Participants will be followed up at 1 week, 1 month, and 3 months post-procedure. At each visit, pain intensity, maximum mouth opening, mandibular movements, and functional limitation will be assessed. The total duration of follow-up for each participant will be 3 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged between 18–50 years -Patients with ASA class 1 and 2 physical status -Patients clinically diagnosed with disc displacement with reduction or disc displacement without reduction according to DC/TMD Axis I diagnostic criteria.
- •Patients who are refractory to conservative management for more than a period of 3 months.
排除标准
- •Local infection at donor or recipient site -Lactating or pregnant women -Previous Temporomandibular joint surgery or intra-articular injections within 6 months -Systemic steroid or immunosuppressive therapy.
研究者
Muhammed Jaseel S V
Yenepoya Dental College