Preoperative CA 19.9 Level Predicts Lymph Node Metastasis in Resectable Adenocarcinoma of the Head of the Pancreas: a Further Plea for Biological Resectability Criteria.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 2,034
- 主要终点
- Quantitative data - Preoperatory levels of CA 19.9 (U/ml)
研究概览
简要总结
In our multicenter retrospective study, preoperative CA 19.9 levels predicts the presence of lymph node metastasis at final histology in patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma .
详细描述
A retrospective analysis have been conducted on more than 2.000 patients underwent pancreatoduodenectomy for pancreatic ductal adenocarcinoma radiologically resectable at the preoperative staging. Preoperatory levels of CA 19.9 were measured in order to identify a relation with nodal involvement at the pathological staging.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients undergone pancreatoduodenectomy
- •No preoperative radiological suspicion of lymph node metastases.
排除标准
- •Age < 18
结局指标
主要结局
Quantitative data - Preoperatory levels of CA 19.9 (U/ml)
时间窗: 20 years
Define relation of quantitative data (CA 19.9 (U/ml)) with nodal positivity at the final pathological report
次要结局
未报告次要终点
研究者
Tommaso Farolfi
Principal investigator
Fondazione Policlinico Universitario Campus Bio-Medico