Normative values of hemodynamic parameters in stable VLBW neonates during first month of life

The objective of this study is to evaluate gestation specific normative data of non-invasive BP and PI inhemodynamically stable VLBW neonates at day during first month of life.

Allneonates will be enrolled at time of admission to NICU. Demographic characteristicsand antenatal details of enrolled infants, including maternal hypertension,fetal growth restriction, umbilical artery Doppler abnormality, chorioamnitis,antenatal steroid cover, and mode of delivery will be recorded on a proforma.Assessment of vital parameters will be made once in a day by single researchnurse, daily during first week, and weekly thereafter till discharge.  At each assessment, heart rate, oxygensaturation (SPO2), capillary refill time (CRT), BP, pulse volume, perfusionindex (PI) and central and peripheral temperature will be recorded.

Sinceinformation on gestation specific longitudinal data is not available in thepublished literature, we are planning to enroll at least 30neonates in each gestation category. Data will be presented as mean (SD) or median (IQR)as per distribution of data.